Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology. 8/e

　　Basic Neurochemistry, Eighth Edition, is the updated version of the outstanding and comprehensive classic text on neurochemistry. For more than forty years, this text has been the worldwide standard for information on the biochemistry of the nervous system, serving as a resource for postgraduate trainees and teachers in neurology, psychiatry, and basic neuroscience, as well as for medical, graduate, and postgraduate students and instructors in the neurosciences.

　　The text has evolved, as intended, with the science. This new edition continues to cover the basics of neurochemistry as in the earlier editions, along with expanded and additional coverage of new research from intracellular trafficking, stem cells, adult neurogenesis, regeneration, and lipid messengers. It contains expanded coverage of all major neurodegenerative and psychiatric disorders, including the neurochemistry of addiction, pain, and hearing and balance; the neurobiology of learning and memory; sleep; myelin structure, development, and disease; autism; and neuroimmunology.
 

Part I: Cellular Neurochemistry and Neural Membranes
Chapter 1. Cell Biology of the Nervous System
Chapter 2. Cell Membrane Structures and Functions
Chapter 3. Membrane Transport
Chapter 4. Electrical Excitability and Ion Channels
Chapter 5. Lipids
Chapter 6. The Cytoskeleton of Neurons and Glia
Chapter 7. Intracellular Trafficking
Chapter 8. Axonal Transport
Chapter 9. Cell Adhesion Molecules
Chapter 10. Myelin Structure and Biochemistry
Chapter 11. Energy Metabolism of the Brain

Part II: Intercellular Signaling
Chapter 12. Synaptic Transmission and Cellular Signaling: An Overview
Chapter 13. Acetylcholine
Chapter 14. Catecholamines
Chapter 15. Serotonin
Chapter 16. Histamine
Chapter 17. Glutamate and Glutamate Receptors
Chapter 18. GABA
Chapter 19. Purinergic Signaling
Chapter 20. Peptides

Part III: Intracellular Signaling
Chapter 21. G Proteins
Chapter 22. Cyclic Nucleotides in the Nervous System
Chapter 23. Phosphoinositides
Chapter 24. Calcium
Chapter 25. Serine and Threonine Phosphorylation
Chapter 26. Tyrosine Phosphorylation
Chapter 27. Transcription Factors in the Central Nervous System

Part IV: Growth, Development and Differentiation
Chapter 28. Development of the Nervous System
Chapter 29. Growth Factors
Chapter 30. Stem Cells in the Nervous System
Chapter 31. Formation and Maintenance of Myelin
Chapter 32. Axonal Growth in the Adult Mammalian Nervous System: Regeneration and

Part V: Cell Injury and Inflammation
Chapter 33. Molecular Mechanisms and Consequences of Immune and Nervous System
Chapter 34. Neuroinflammation
Chapter 35. Brain Ischemia and Reperfusion: Cellular and Molecular Mechanisms in Stroke
Chapter 36. Lipid Mediators: Eicosanoids, Docosanoids and Platelet-Activating Factor
Chapter 37. Apoptosis and Necrosis

Part VI: Inherited and Neurodegenerative Diseases
Chapter 38. Peripheral Neuropathy: Neurochemical and Molecular Mechanisms
Chapter 39. Diseases Involving Myelin
Chapter 40. The Epilepsies: Phenotypes and Mechanisms
Chapter 41. Genetics of Neurodegenerative Diseases
Chapter 42. Disorders of Amino Acid Metabolism
Chapter 43. Inborn Metabolic Defects of Lysosomes, Peroxisomes, Carbohydrates, Fatty Acids and Mitochondria
Chapter 44. Disorders of Muscle Excitability
Chapter 45. Motor Neuron Diseases
Chapter 46. Neurobiology of Alzheimer’s Disease
Chapter 47. Synucleinopathies and Tauopathies
Chapter 48. Cellular and Molecular Basis of Neurodegeneration in the CAG–Polyglutamine
Chapter 49. Neurotransmitters and Disorders of the Basal Ganglia
Chapter 50. Molecular Basis of Prion Diseases

Part VII: Sensory Transduction
Chapter 51. Molecular Biology of Vision
Chapter 52. Molecular Basis of Olfaction and Taste
Chapter 53. Molecular Biology of Hearing and Balance
Chapter 54. Pain

Part VIII: Neural Processing and Behavior
Chapter 55. Endocrine Effects on the Brain and Their Relationship to Behavior
Chapter 56. Learning and Memory
Chapter 57. The Neurochemistry of Sleep and Wakefulness
Chapter 58. The Neurochemistry of Schizophrenia
Chapter 59. The Neurochemistry of Autism
Chapter 60. Neurobiology of Severe Mood and Anxiety Disorders
Chapter 61. Addiction

Glossary
Index

 

編者簡介

Scott Brady

　　Affiliations and Expertise
　　Head, Department of Anatomy and Cell Biology, University of Illinois, Chicago, Illinois, USA University of Illinois, Chicago IL

George Siegel

　　Affiliations and Expertise

　　Emeritus Professor of Neruology, Loyola University Chicago Stritch School of Medicine; Chief of Neurology Service (retired), Edward Hines, Jr. Veterans Affairs Hospital, Chicago, IL, USA

R. Wayne Albers

　　Affiliations and Expertise
　　National Institutes of Health, Bethesda MD, USA

Donald Price

　　Affiliations and Expertise
　　The Johns Hopkins University School of Medicine, Baltimore MD